The San Diego Stock Exchange Index closed lower Friday at 121.69, down 0.29 percent from Thursday. Declining issues beat advancers 45 to 38, and 56 issues were unchanged. Cymer Inc. (Nasdaq: CYMI) was the top dollar gainer, up 75 cents to $88.51. Pricesmart Inc. (Nasdaq: PSMT) was the top dollar loser, down $3.30 to $75.27. For the complete, updated San Diego Stock Exchange Index visit sddt.com/stocks.