The San Diego Stock Exchange Index closed lower Thursday at 122.04, down 0.50 percent from Wednesday. Declining issues beat advancers 50 to 34, and 55 issues were unchanged. Santarus Inc. (Nasdaq: SNTS) was the top dollar gainer, up 54 cents to $10.40. Pricesmart Inc. (Nasdaq: PSMT) was the top dollar loser, down 95 cents to $74.08. For the complete, updated San Diego Stock Exchange Index visit sddt.com/stocks.