The San Diego Stock Exchange Index closed lower Monday at 126.22, down 0.47 percent from Friday. Declining issues beat advancers 48 to 32, and 59 issues were unchanged. Optimer Pharmaceuticals Inc. (Nasdaq: OPTR) was the top dollar gainer, up $1.18 to $10.43. Illumina Inc. (Nasdaq: ILMN) was the top dollar loser, down $3.86 to $50.90. For the complete, updated San Diego Stock Exchange Index visit sddt.com/stocks.