The San Diego Stock Exchange Index closed lower Friday at 120.30, down 1.06 percent from Thursday. Declining issues beat advancers 52 to 26, and 62 issues were unchanged.
Ligand Pharmaceuticals (Nasdaq: LGND) was the top dollar gainer, up 69 cents to $16.18.
Encore Capital Group Inc. (Nasdaq: ECPG) was the top dollar loser, down $2.19 to $26.62.
For the complete, updated San Diego Stock Exchange Index visit sddt.com/stocks.
A Los Angeles judge has tentatively ruled against a former computer specialist who sued Jet Propulsion Laboratory alleging he was laid off because he advocated his belief in intelligent design while at work.
Environmental groups have filed a second lawsuit to stop a controversial plan to pump water from Mojave Desert aquifers to cities across the state.
Authorities say the man suspected of shooting an off-duty officer and who was killed in a gunbattle with San Diego police late Halloween night was a former firefighter facing charges of sex with a minor.
Orange County prosecutors say a former Fullerton police officer will serve probation after destroying an audio recording of conversations he had with a suspect who later committed suicide in jail.
Two former mayors of a seaside Northern California city defended the decision to oust a critic who gave a Nazi salute from a city council meeting.
Police and the family of a popular small business owner in Oakland are searching for the slain man's killer.
A gang member whose jury recommended the death penalty is due for sentencing in the shooting death of an up-and-coming high school football player.
A fired Southern California science teacher is begging for her job back, telling an administrative hearing she was desperate for money when she decided to perform in pornographic videos.
Authorities say one man is dead and another hospitalized after a car-to-car shooting in Baldwin Park.
The newest panda at the San Diego Zoo has a new tooth and a clean bill of health and soon it will have a new name too.
The birds at La Jolla Cove are causing a stink.
A California nurse has pleaded no contest to felony patient abuse and agreed to help in the prosecution of her nursing home supervisor.
The USS Anchorage will be commissioned in its namesake city on May 4.
The aging founder of the Crystal Cathedral is in court seeking more than $5 million from the ministry he built from scratch in a dispute that has delayed millions in payments to creditors left short-handed when the church filed for bankruptcy two years ago.