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Michael Chang

Chief Executive Officer

Optimer Pharmaceuticals

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Optimer Pharmaceuticals

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About: Michael Chang

Optimer Pharmaceuticals Chief Executive Officer Michael Chang is optimistic that larger venture capital firms won't be overlooking the company for long.

Started in 2000 by Chang and fellow researchers Chi-Huey Wong and Samuel Danishefky, Optimer specializes in carbohydrate chemistry and drugs that combat cancer, arthritis and immune disorders.

The company is especially excited about a new drug being developed to fight clostridium difficile bacteria, which causes a potentially deadly form of diarrhea that some health experts say is on the rise in hospitals and nursing homes. The drug had some success in Phase 2 clinical trials and the Food and Drug Administration approved expanded tests through 2008.

"The FDA thinks this is a very important topic, so we developed this product on a fast track," Chang said. "The product is a unique chemical structure, a new mechanism, we think that's really vital. It's a very interesting product."

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