San Diego’s Top Influentials highlights the Who’s Who in San Diego business, profiling the top newsmakers of 2008. This year we focus on the leaders in Biotech, Tech & Defense; Construction; Finance; Law and Business & Consumer Services; and Real Estate.
Since 1886, The Daily Transcript has seen and reported on many significant changes to San Diego’s economic landscape, many of which stem from the remarkable ideas and contributions of individuals. We pay tribute to these prominent newsmakers — San Diego’s movers and shakers — with a special salute to the Top Influentials.
Since 1886, The Daily Transcript has seen and reported on many significant changes to San Diego’s economic landscape, many of which stem from the remarkable ideas and numerous contributions of single individuals. These individuals have impacted our lives, our communities, our economy. Now, we pay tribute to these prominent newsmakers – San Diego’s movers and shakers – with a special salute to the 120 Top Influentials. 
As The Daily Transcript celebrates its 120th year in print, our editorial board -- with help from the San Diego Historical Society -- reflects back on our region’s rich history. In this feature, we pay tribute to some of the pioneers who played an integral part in laying the foundation for San Diego’s future growth. Read more about the contributions these individuals have made as the Transcript takes a brief look back through time. 
In celebration of The Daily Transcript's 120th Anniversary, we pay tribute to the prominent business leaders -- past and present -- who have impacted the region. The Daily Transcript thanks its sponsors for participating in this anniversary publication. 
10210 Genetic Center Dr.
San Diego, CA 92121
Gen-Probe is no stranger to recognition, and CEO and President Henry Nordhoff is keeping it that way.
In 1985, Gen-Probe was the first nucleic acid diagnostic company to use DNA probe technology. Today, it strives to be the world leader in molecular diagnostics for human disease. Under Nordhoff's stewardship, Gen-Probe has been recognized for its efforts by top national business publications, including Forbes "200 Best Small Companies," Business Week: "The Hot 100 Growth Companies," Wired 40 -- Companies Driving the Global Economy, the Wall Street Journal's Shareholders Scorecard Best Performers and more.
Gen-Probe also was named a Best Company to Work For in 2005 by California AARP and the San Diego Business Journal. Perhaps most notably, Gen-Probe received the 2004 National Medal of Technology Laureate by President George W. Bush for its pioneering work developing disease testing for donated blood supply.
Nordhoff is a member of the board of directors of Mannkind Corp.