Saturday, November 21, 2009 
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San Diego’s Top Influentials highlights the Who’s Who in San Diego business, profiling the top newsmakers of 2008. This year we focus on the leaders in Biotech, Tech & Defense; Construction; Finance; Law and Business & Consumer Services; and Real Estate.
Since 1886, The Daily Transcript has seen and reported on many significant changes to San Diego’s economic landscape, many of which stem from the remarkable ideas and contributions of individuals. We pay tribute to these prominent newsmakers — San Diego’s movers and shakers — with a special salute to the Top Influentials.
Since 1886, The Daily Transcript has seen and reported on many significant changes to San Diego’s economic landscape, many of which stem from the remarkable ideas and numerous contributions of single individuals. These individuals have impacted our lives, our communities, our economy. Now, we pay tribute to these prominent newsmakers – San Diego’s movers and shakers – with a special salute to the 120 Top Influentials.
As The Daily Transcript celebrates its 120th year in print, our editorial board -- with help from the San Diego Historical Society -- reflects back on our region’s rich history. In this feature, we pay tribute to some of the pioneers who played an integral part in laying the foundation for San Diego’s future growth. Read more about the contributions these individuals have made as the Transcript takes a brief look back through time.
In celebration of The Daily Transcript's 120th Anniversary, we pay tribute to the prominent business leaders -- past and present -- who have impacted the region. The Daily Transcript thanks its sponsors for participating in this anniversary publication.
10350 N Torrey Pines Rd.
La Jolla, CA 92037
Catherine "Kitty" Mackey heads up Pfizer Inc.'s La Jolla campus, with 1,000 employees and a million square feet of office and laboratory space.
Mackey came to Pfizer La Jolla after leading Genomic and Proteomic Sciences at the pharmaceutical giant's 6,000-employee campus in Groton, Conn., and has been at Pfizer La Jolla since 2001. More recently, the company has gone through a number of changes at its highest levels -- it hired a new chief executive officer, Jeffrey Kindler, in July and there have been shakeups at the executive level throughout the summer. Pfizer scientists also are scrambling to create a drug to replace Lipitor, the company's blockbuster cholesterol drug whose patent is set to expire soon.
At Pfizer La Jolla, the focus is on researching compounds and developing market-ready drugs. Much of that research is focused on cancer drugs, as well as opthamology, diabetes and virology.