San Diego’s Top Influentials highlights the Who’s Who in San Diego business, profiling the top newsmakers of 2008. This year we focus on the leaders in Biotech, Tech & Defense; Construction; Finance; Law and Business & Consumer Services; and Real Estate.
Since 1886, The Daily Transcript has seen and reported on many significant changes to San Diego’s economic landscape, many of which stem from the remarkable ideas and contributions of individuals. We pay tribute to these prominent newsmakers — San Diego’s movers and shakers — with a special salute to the Top Influentials.
Since 1886, The Daily Transcript has seen and reported on many significant changes to San Diego’s economic landscape, many of which stem from the remarkable ideas and numerous contributions of single individuals. These individuals have impacted our lives, our communities, our economy. Now, we pay tribute to these prominent newsmakers – San Diego’s movers and shakers – with a special salute to the 120 Top Influentials. 
As The Daily Transcript celebrates its 120th year in print, our editorial board -- with help from the San Diego Historical Society -- reflects back on our region’s rich history. In this feature, we pay tribute to some of the pioneers who played an integral part in laying the foundation for San Diego’s future growth. Read more about the contributions these individuals have made as the Transcript takes a brief look back through time. 
In celebration of The Daily Transcript's 120th Anniversary, we pay tribute to the prominent business leaders -- past and present -- who have impacted the region. The Daily Transcript thanks its sponsors for participating in this anniversary publication. 
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Kleanthis Xanthopoulos has had a dual love of science and business since he was a teenager in Greece studying in a science program and trading leather goods in his spare time. For the past six years, he has been exercising both of those infatuations as the founder and CEO of Anadys Pharmaceuticals (Nasdaq: ANDS), and now he wants to try and do it again.
The recent winner of Ernst & Young's Entrepreneur of the Year Award in Health Sciences, Xanthopoulos announced that he'll step down as the head of Anadys and work for Enterprise Partners, where he hopes to provide funding to build "more companies like Anadys."
"I love this industry; I want to influence the industry on multiple levels," Xanthopoulos said. "I'm more interested in translating science into business. If I'm fortunate enough to create a company that's as good as Anadys and do it again then I will be truly grateful and very satisfied."