San Diego’s Top Influentials highlights the Who’s Who in San Diego business, profiling the top newsmakers of 2008. This year we focus on the leaders in Biotech, Tech & Defense; Construction; Finance; Law and Business & Consumer Services; and Real Estate.
Since 1886, The Daily Transcript has seen and reported on many significant changes to San Diego’s economic landscape, many of which stem from the remarkable ideas and contributions of individuals. We pay tribute to these prominent newsmakers — San Diego’s movers and shakers — with a special salute to the Top Influentials.
Since 1886, The Daily Transcript has seen and reported on many significant changes to San Diego’s economic landscape, many of which stem from the remarkable ideas and numerous contributions of single individuals. These individuals have impacted our lives, our communities, our economy. Now, we pay tribute to these prominent newsmakers – San Diego’s movers and shakers – with a special salute to the 120 Top Influentials. 
As The Daily Transcript celebrates its 120th year in print, our editorial board -- with help from the San Diego Historical Society -- reflects back on our region’s rich history. In this feature, we pay tribute to some of the pioneers who played an integral part in laying the foundation for San Diego’s future growth. Read more about the contributions these individuals have made as the Transcript takes a brief look back through time. 
In celebration of The Daily Transcript's 120th Anniversary, we pay tribute to the prominent business leaders -- past and present -- who have impacted the region. The Daily Transcript thanks its sponsors for participating in this anniversary publication. 
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When Magda Marquet and her husband Francois Ferre left high-paying biotech jobs in 1998 to co-create their own company, Althea Technologies Inc., their friends called them crazy.
With their combined expertise -- Marquet had patented several new methods to produce clinical-grade DNA as executive director of pharmaceutical development at Vical Inc. (Nasdaq: VICL), and Ferre had made a name for himself in cancer research and HIV clinical development at Cytometrics and The Immune Response Corp. -- the couple got off to a good start.