San Diego’s Top Influentials highlights the Who’s Who in San Diego business, profiling the top newsmakers of 2008. This year we focus on the leaders in Biotech, Tech & Defense; Construction; Finance; Law and Business & Consumer Services; and Real Estate.
Since 1886, The Daily Transcript has seen and reported on many significant changes to San Diego’s economic landscape, many of which stem from the remarkable ideas and contributions of individuals. We pay tribute to these prominent newsmakers — San Diego’s movers and shakers — with a special salute to the Top Influentials.
Since 1886, The Daily Transcript has seen and reported on many significant changes to San Diego’s economic landscape, many of which stem from the remarkable ideas and numerous contributions of single individuals. These individuals have impacted our lives, our communities, our economy. Now, we pay tribute to these prominent newsmakers – San Diego’s movers and shakers – with a special salute to the 120 Top Influentials. 
As The Daily Transcript celebrates its 120th year in print, our editorial board -- with help from the San Diego Historical Society -- reflects back on our region’s rich history. In this feature, we pay tribute to some of the pioneers who played an integral part in laying the foundation for San Diego’s future growth. Read more about the contributions these individuals have made as the Transcript takes a brief look back through time. 
In celebration of The Daily Transcript's 120th Anniversary, we pay tribute to the prominent business leaders -- past and present -- who have impacted the region. The Daily Transcript thanks its sponsors for participating in this anniversary publication. 
10901 North Torrey Pines Rd.
La Jolla, CA 92037
Karin Eastham serves as executive vice president and chief operating officer of the Burnham Institute for Medical Research, a nonprofit corporation engaged in basic biomedical research and home to three research centers: An NCI-designated Cancer Center, the Del E. Webb Center for Neuroscience and Aging Research, and the Infectious and Inflammatory Disease Center.
The Burnham institute has approximately 740 employees and an annual operating budget of about $90 million. It is based in La Jolla, which Eastham believes is a unique center of excellence for biotech and pharmaceutical work. The breadth of different industries working in La Jolla, a very strong job market and excellent infrastructure has made it a popular area for the high-tech industry.
Eastham has more than 25 years' experience in financial and operations management, primarily in life sciences companies. She also serves on the boards of directors of Tercica Inc., Illumina Inc, SGX Pharmaceuticals Inc., Cyntellect Inc. and Amylin Pharmaceuticals Inc.